How can I benefit from ADCETRIS?
Before making decisions about your treatment, see how others have responded to ADCETRIS
The science of ADCETRIS treatment
ADCETRIS is not like traditional chemotherapy. It is an antibody drug conjugate made up of 3 parts: an antibody, a drug, and a linker.
Antibody
An antibody that finds CD30, a protein on the surface of certain cells. Antibodies are proteins made by the body’s immune system. The antibody that makes up ADCETRIS is made in a laboratory.
Drug
A drug that is designed to cause cell death.
Linker
A linker that attaches the drug to the antibody and releases the drug inside the cell.
How does ADCETRIS work?
Step 1
ADCETRIS aims to attach to cells that have a protein on their surface called CD30.
Step 2
Once attached, ADCETRIS is brought into the cell and released.
Step 3
The drug stops the cell from being able to grow and divide, causing the cell to die.
CD30 is found on cancer cells of peripheral T-cell lymphomas, including these types:
- Adult T-cell lymphoma/leukemia
- Angioimmunoblastic T-cell lymphoma
- Enteropathy-associated T-cell lymphoma
- Peripheral T-cell lymphoma not otherwise specified
- Cutaneous T-cell lymphomas
- Systemic anaplastic large cell lymphoma
ADCETRIS targets a protein called CD30 found on the surface of cells, including peripheral T-cell lymphoma cells. Even though ADCETRIS is a CD30-directed treatment, it can still affect normal cells and can cause side effects. Talk to your doctor if you have more questions about possible side effects.